The following table illustrates the major research centers of the Defence Research and Development Organisation (DRDO) −
| Laboratory Name | Area of Research | Location |
| Aerial Delivery Research & Development Establishment (ADRDE) | Parachutes & Aerial Systems | Agra |
| Vehicles Research & Development Establishment (VRDE) | Wheeled Vehicles | Ahmednagar |
| Naval Materials Research Laboratory (NMRL) | Naval Materials | Ambernath |
| Integrated Test Range (ITR) | Missile Testing | Balasore |
| Proof and Experimental Establishment (PXE) | Armament Testing | Balasore |
| Aeronautical Development Establishment (ADE) | Aeronautics | Bengaluru |
| Centre for Air Borne System (CABS) | Air-Borne Systems | Bengaluru |
| Centre for Artificial Intelligence & Robotics (CAIR) | Artificial Intelligence & Robotics | Bengaluru |
| Defence Avionics Research Establishment (DARE) | Avionics | Bengaluru |
| Defence Bio-engineering &Electromedical Laboratory (DEBEL) | Bio-engineering | Bengaluru |
| Gas Turbine Research Establishment (GTRE) | Gas Turbine | Bengaluru |
| Electronics & Radar Development Establishment (LRDE) | Radars | Bengaluru |
| Microwave Tube Research & Development Centre (MTRDC) | Microwave Devices | Bengaluru |
| Snow and Avalanche Study Establishment (SASE) | Snow and Avalanche | Chandigarh |
| Terminal Ballistics Research Laboratory (TBRL) | Ballistics | Chandigarh |
| Combat Vehicles Research & Development Establishment (CVRDE) | Combat Vehicles | Chennai |
| Defence Electronics Applications Laboratory (DEAL) | Electronics & Communication Systems | Dehradun |
| Instruments Research & Development Establishment (IRDE) | Electronics & Optical Systems | Dehradun |
| Centre for Fire, Explosives & Environment Safety (CFEES) | Explosives | Delhi |
| Defence Institute of Physiology & Allied Sciences (DIPAS) | Physiology | Delhi |
| Defence Institute of Psychological Research (DIPR) | Psychological Research | Delhi |
| Defence Terrain Research Laboratory (DTRL) | Terrain Research | Delhi |
| Institute of Nuclear Medicines & Allied Sciences (INMAS) | Nuclear Medicine | Delhi |
| Joint Cipher Bureau (JCB) | Cipher Systems | Delhi |
| Laser Science & Technology Centre (LASTEC) | Laser Technology | Delhi |
| Scientific Analysis Group (SAG) | Cryptology | Delhi |
| Solid State Physics Laboratory (SSPL) | Solid- State/ Semiconductor Materials | Delhi |
| Defence Research & Development Establishment (DRDE) | Chemical & Biological Warfare | Gwalior |
| Defence Institute of Bio-Energy Research (DIBER) | Bio-Energy | Haldwani |
| Advanced Numerical Research & Analysis Group (ANURAG) | Computational System | Hyderabad |
| Advanced Systems Laboratory (ASL) | Missiles & Strategic Systems | Hyderabad |
| Centre for High Energy Systems and Sciences (CHESS) | High Energy Weapons | Hyderabad |
| Defence Electronics Research Laboratory (DLRL) | Electronic Warfare | Hyderabad |
| Defence Metallurgical Research Laboratory (DMRL) | Metallurgy | Hyderabad |
| Defence Research & Development Laboratory (DRDL) | Missile & Strategic Systems | Hyderabad |
| Research Centre Imarat (RCI) | Missile & Strategic Systems | Hyderabad |
| Defence Laboratory (DL) | Camouflaging and Isotopes | Jodhpur |
| Defence Materials & Stores Research & Development Establishment (DMSRDE) | Textiles, Polymers & Composites | Kanpur |
| Naval Physical & Oceanographic Laboratory (NPOL) | Sonar Systems | Kochi |
| Defence Institute of High Altitude Research (DIHAR) | High Altitude Agroanimal Research | Leh |
| Defence Food Research Laboratory (DFRL) | Food Research | Mysore |
| Armaments Research & Development Establishment (ARDE) | Armaments | Pune |
| High Energy Materials Research Laboratory (HEMRL) | High Energy Materials | Pune |
| Research & Development Establishment (Engrs) (R&DE[E]) | Engineering Systems & Weapon Platforms | Pune |
| Defence Research Laboratory (DRL) | Health & Hygiene | Tezpur |
| Naval Science & Technological Laboratory (NSTL) | Underwater Weapons | Visakhapatnam |
